Chemicals and Drugs

Mepartricin

Polyene macrolide antibiotic with unknown composition. It is obtained from Streptomyces aureofaciens. It is used as an antifungal agent, an antiprotozoal agent, and in the treatment of BENIGN PROSTATIC HYPERTROPHY.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Polyene macrolide antibiotic with unknown composition. It is obtained from Streptomyces aureofaciens. It is used as an antifungal agent, an antiprotozoal agent, and in the treatment of BENIGN PROSTATIC HYPERTROPHY.

Chemical Identity

Chemical Information

Molecular Formula
C60H88N2O19
Molecular Weight
1141.3 g/mol
IUPAC Name
methyl (19E,21E,23Z,25Z,27E,29E,31E)-33-[(2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy-1,3,5,7,9,13,37-heptahydroxy-17-[5-hydroxy-7-[4-(methylamino)phenyl]-7-oxoheptan-2-yl]-18-methyl-11,15-dioxo-16,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylate
InChIKey
GVEVTKSEPQUIJA-PLDHRHJXSA-N
SMILES
C[C@@H]1[C@H]([C@@H]([C@@H]([C@@H](O1)OC\2CC3C(C(CC(O3)(CC(CC(CC(CC(CC(=O)CC(CC(=O)OC(C(/C=C/C=C/C=C\C=C/C=C/C=C/C=C2)C)C(C)CCC(CC(=O)C4=CC=C(C=C4)NC)O)O)O)O)O)O)O)O)C(=O)OC)O)N)O
MeSH Unique ID
D008613
Source
PubChem CID 6479653

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

8 entry terms
  • Methyl Partricin
  • Methylpartricin
  • Mepartricin A
  • Mepartricin B
  • SPA-S 160
  • Tricandil
  • SPA S 160
  • SPAS 160

MeSH Record

Aspects Covered

26 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(81); was see under POLYENES 1981-90; was METHYL PARTRICIN see under POLYENES 1976-80

MeSH Record

Previous Indexing

  • Polyenes (1974-1975)

MeSH Hierarchy

Tree Numbers

  1. D02w.455w.326.271w.665w.400w
  2. D02w.540w.505w.497w

AMA Style

References

  1. National Library of Medicine. Mepartricin. Medical Subject Headings (MeSH). 2026. Unique ID D008613. http://id.nlm.nih.gov/mesh/2026/D008613
  2. Mepartricin. In: Wikipedia. https://en.wikipedia.org/wiki/Mepartricin
  3. Mepartricin. In: Wikidata. https://www.wikidata.org/wiki/Q194535
  4. Mepartricin. In: PubChem Compound. CID 6479653. https://pubchem.ncbi.nlm.nih.gov/compound/6479653