Chemicals and Drugs

Membrane Cofactor Protein

A ubiquitously expressed complement receptor that binds COMPLEMENT C3B and COMPLEMENT C4B and serves as a co-factor for their inactivation by COMPLEMENT FACTOR I. It also interacts with a wide variety of pathogens and mediates the immune response.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A ubiquitously expressed complement receptor that binds COMPLEMENT C3B and COMPLEMENT C4B and serves as a co-factor for their inactivation by COMPLEMENT FACTOR I. It also interacts with a wide variety of pathogens and mediates the immune response.

MeSH Record

Classification

Broader headings

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

7 entry terms
  • Antigens, CD46
  • CD46 Antigen
  • CD46 Antigens
  • Trophoblast-Leukocyte Common Antigen
  • Antigen, CD46
  • Common Antigen, Trophoblast-Leukocyte
  • Trophoblast Leukocyte Common Antigen

MeSH Record

Aspects Covered

19 allowable subheadings

Indexed with the subheadings administration & dosage, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.

MeSH Record

History Note

2018 (1987)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.124w.486.274.920.124
  2. D12.776w.543w.750w.705w.833.124

AMA Style

References

  1. National Library of Medicine. Membrane Cofactor Protein. Medical Subject Headings (MeSH). 2026. Unique ID D051916. http://id.nlm.nih.gov/mesh/2026/D051916
  2. Membrane Cofactor Protein. In: Wikidata. https://www.wikidata.org/wiki/Q24784728