Structured Summary
Abstract
A member of the tumor necrosis factor receptor superfamily that is specific for 4-1BB LIGAND. It is found in a variety of immune cell types including activated T-LYMPHOCYTES; NATURAL KILLER CELLS; and DENDRITIC CELLS. Activation of the receptor on T-LYMPHOCYTES plays a role in their expansion, production of cytokines and survival. Signaling by the activated receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.
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Synonyms
13 entry terms
- 4-1BB Receptor
- 4-1BB Receptors
- Antigens, CD137
- CD137 Antigen
- CD137 Antigens
- TNFRSF9 Receptor
- Tumor Necrosis Factor Receptor Superfamily, Member 9
- 4 1BB Receptor
- 4 1BB Receptors
- Antigen, CD137
- Receptor, 4-1BB
- Receptor, TNFRSF9
- Receptors, 4-1BB
MeSH Record
Aspects Covered
19 allowable subheadings
Indexed with the subheadings administration & dosage, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.
MeSH Record
History Note
2018 (1993)
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AMA Style
References
- National Library of Medicine. Member 9 Tumor Necrosis Factor Receptor Superfamily. Medical Subject Headings (MeSH). 2026. Unique ID D053261. http://id.nlm.nih.gov/mesh/2026/D053261
- Member 9 Tumor Necrosis Factor Receptor Superfamily. In: Wikidata. https://www.wikidata.org/wiki/Q24771574