Chemicals and Drugs

Meiotic Recombination Protein SPO11

An endodeoxyribonuclease that functions as part of a DNA TOPOISOMERASE II complex to create DOUBLE-STRAND DNA BREAKS for initiating HOMOLOGOUS RECOMBINATION in MEIOSIS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An endodeoxyribonuclease that functions as part of a DNA TOPOISOMERASE II complex to create DOUBLE-STRAND DNA BREAKS for initiating HOMOLOGOUS RECOMBINATION in MEIOSIS.

MeSH Record

Classification

Broader headings

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MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2026 (1999)

MeSH Hierarchy

Tree Numbers

  1. D08.811w.277w.352w.335w.350w.675
  2. D08.811w.277w.352w.355w.325w.650

AMA Style

References

  1. National Library of Medicine. Meiotic Recombination Protein SPO11. Medical Subject Headings (MeSH). 2026. Unique ID D000099257. http://id.nlm.nih.gov/mesh/2026/D000099257
  2. Meiotic Recombination Protein SPO11. In: Wikidata. https://www.wikidata.org/wiki/Q83163487