Chemicals and Drugs

Medrogestone

6,17-Dimethylpregna-4,6-diene-3,20-dione. A synthetic progestational hormone with actions similar to those of progesterone. It is used in the treatment of menstrual irregularities and has also been employed in the treatment of prostatic hypertrophy and endometrial carcinoma.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

6,17-Dimethylpregna-4,6-diene-3,20-dione. A synthetic progestational hormone with actions similar to those of progesterone. It is used in the treatment of menstrual irregularities and has also been employed in the treatment of prostatic hypertrophy and endometrial carcinoma.

Chemical Identity

Chemical Information

Molecular Formula
C23H32O2
Molecular Weight
340.5 g/mol
CAS Registry No.
977-79-7
IUPAC Name
(8R,9S,10R,13S,14S,17S)-17-acetyl-6,10,13,17-tetramethyl-2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-3-one
InChIKey
HCFSGRMEEXUOSS-JXEXPEPMSA-N
SMILES
CC1=C[C@@H]2[C@H](CC[C@]3([C@H]2CC[C@]3(C)C(=O)C)C)[C@@]4(C1=CC(=O)CC4)C
MeSH Unique ID
D008524
Source
PubChem CID 9949848

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

3 entry terms
  • Colpro
  • Colprone
  • Prothil

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

a synthetic progestational hormone

MeSH Record

History Note

91(72); was see under PREGNADIENES 1972-90

MeSH Record

Previous Indexing

  • Pregnadienes (1966-1971)
  • Progestational Hormones (1966-1971)

MeSH Hierarchy

Tree Number

  1. D04w.210.500w.745.432w.481w

AMA Style

References

  1. National Library of Medicine. Medrogestone. Medical Subject Headings (MeSH). 2026. Unique ID D008524. http://id.nlm.nih.gov/mesh/2026/D008524
  2. Medrogestone. In: Wikipedia. https://en.wikipedia.org/wiki/Medrogestone
  3. Medrogestone. In: Wikidata. https://www.wikidata.org/wiki/Q6807285
  4. Medrogestone. In: PubChem Compound. CID 9949848. https://pubchem.ncbi.nlm.nih.gov/compound/9949848