Chemicals and Drugs

Meclizine

A histamine H1 antagonist used in the treatment of motion sickness, vertigo, and nausea during pregnancy and radiation sickness.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A histamine H1 antagonist used in the treatment of motion sickness, vertigo, and nausea during pregnancy and radiation sickness.

Chemical Identity

Chemical Information

Molecular Formula
C25H27ClN2
Molecular Weight
390.9 g/mol
CAS Registry No.
569-65-3
IUPAC Name
1-[(4-chlorophenyl)-phenylmethyl]-4-[(3-methylphenyl)methyl]piperazine
InChIKey
OCJYIGYOJCODJL-UHFFFAOYSA-N
SMILES
CC1=CC(=CC=C1)CN2CCN(CC2)C(C3=CC=CC=C3)C4=CC=C(C=C4)Cl
MeSH Unique ID
D008468
Source
PubChem CID 4034

MeSH Record

Classification

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

19 entry terms
  • Meclozine
  • Parachloramine
  • Agyrax
  • Antivert
  • Bonamine
  • Bonine
  • Chiclida
  • D-Vert
  • Histametizyn
  • Meclizine Dihydrochloride
  • Meclizine Hydrochloride
  • Meclizine Monohydrochloride
  • Ru-Vert-M
  • D Vert
  • DVert
  • Dihydrochloride, Meclizine
  • Hydrochloride, Meclizine
  • Monohydrochloride, Meclizine
  • Ru Vert M

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Meclizine. Medical Subject Headings (MeSH). 2026. Unique ID D008468. http://id.nlm.nih.gov/mesh/2026/D008468
  2. Meclizine. In: Wikipedia. https://en.wikipedia.org/wiki/Meclizine
  3. Meclizine. In: Wikidata. https://www.wikidata.org/wiki/Q386441
  4. Meclizine. In: PubChem Compound. CID 4034. https://pubchem.ncbi.nlm.nih.gov/compound/4034