Structured Summary
Abstract
A transmembrane domain-containing matrix metalloproteinase. It is synthesized as an inactive zymogen that is activated by the action of PROPROTEIN CONVERTASES such as FURIN. Matrix metalloproteinase 14 plays a direct role in the cleavage of proteins in the pericellular environment. In addition, it can function indirectly by enzymatically activating the proprotein form of MATRIX METALLOPROTEINASE 15.
MeSH Record
Classification
Broader headings
Related Concepts
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MeSH Record
Synonyms
17 entry terms
- MMP-14 Metalloproteinase
- MMP-X1 Protein
- MMP14 Metalloproteinase
- MT-MMP-1
- MT1-MMP
- MT1-Matrix Metalloproteinase
- Membrane-Type 1 Matrix Metalloproteinase
- Membrane-Type Matrix Metalloproteinase 1
- MMP 14 Metalloproteinase
- MMP X1 Protein
- MT1 Matrix Metalloproteinase
- Membrane Type 1 Matrix Metalloproteinase
- Membrane Type Matrix Metalloproteinase 1
- Metalloproteinase 14, Matrix
- Metalloproteinase, MMP-14
- Metalloproteinase, MMP14
- Metalloproteinase, MT1-Matrix
MeSH Record
Aspects Covered
28 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2007(1994)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Matrix Metalloproteinase 14. Medical Subject Headings (MeSH). 2026. Unique ID D053511. http://id.nlm.nih.gov/mesh/2026/D053511
- Matrix Metalloproteinase 14. In: Wikidata. https://www.wikidata.org/wiki/Q24781668