Diseases

Marchiafava-Bignami Disease

A neurodegenerative condition that is characterized by demyelination or necrosis of the CORPUS CALLOSUM. Symptoms include DEPRESSION; PARANOIA; DEMENTIA; SEIZURES; and ATAXIA which can progress to COMA and death in a few months. Marchiafava-Bignami syndrome is seen often in alcoholics but has been found in non-alcoholics as well.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A neurodegenerative condition that is characterized by demyelination or necrosis of the CORPUS CALLOSUM. Symptoms include DEPRESSION; PARANOIA; DEMENTIA; SEIZURES; and ATAXIA which can progress to COMA and death in a few months. Marchiafava-Bignami syndrome is seen often in alcoholics but has been found in non-alcoholics as well.

MeSH Record

Classification

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MeSH Record

Synonyms

3 entry terms
  • Marchiafava-Bignami Syndrome
  • Marchiafava Bignami Disease
  • Marchiafava Bignami Syndrome

MeSH Record

Aspects Covered

35 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

History Note

2008

MeSH Record

Previous Indexing

  • Demyelinating Diseases (1965-2007)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Marchiafava-Bignami Disease. Medical Subject Headings (MeSH). 2026. Unique ID D054319. http://id.nlm.nih.gov/mesh/2026/D054319
  2. Marchiafava-Bignami Disease. In: Wikipedia. https://en.wikipedia.org/wiki/Marchiafava%E2%80%93Bignami_disease
  3. Marchiafava-Bignami Disease. In: Wikidata. https://www.wikidata.org/wiki/Q94796