Chemicals and Drugs

Maprotiline

A bridged-ring tetracyclic antidepressant that is both mechanistically and functionally similar to the tricyclic antidepressants, including side effects associated with its use.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A bridged-ring tetracyclic antidepressant that is both mechanistically and functionally similar to the tricyclic antidepressants, including side effects associated with its use.

Chemical Identity

Chemical Information

Molecular Formula
C20H23N
Molecular Weight
277.4 g/mol
CAS Registry No.
10262-69-8
IUPAC Name
N-methyl-3-(1-tetracyclo[6.6.2.02,7.09,14]hexadeca-2,4,6,9,11,13-hexaenyl)propan-1-amine
InChIKey
QSLMDECMDJKHMQ-UHFFFAOYSA-N
SMILES
CNCCCC12CCC(C3=CC=CC=C31)C4=CC=CC=C24
MeSH Unique ID
D008376
Source
PubChem CID 4011

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

24 entry terms
  • Dibencycladine
  • Maprotilin
  • N-Methyl-9,10-ethanoanthracene-9(10H)-propylamine
  • Ba-34,276
  • Deprilept
  • Ludiomil
  • Maprolu
  • Maprotilin Holsten
  • Maprotilin-TEVA
  • Maprotilin-neuraxpharm
  • Maprotilin-ratiopharm
  • Maprotiline Hydrochloride
  • Maprotiline Mesylate
  • Mirpan
  • Novo-Maprotiline
  • Psymion
  • maprotilin von ct
  • Ba34,276
  • Hydrochloride, Maprotiline
  • Maprotilin TEVA
  • Maprotilin neuraxpharm
  • Maprotilin ratiopharm
  • Mesylate, Maprotiline
  • Novo Maprotiline

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(75); was see under ANTHRACENES 1975-90

MeSH Record

Previous Indexing

  • Anthracenes (1972-1974)
  • Propylamines (1972-1974)

MeSH Hierarchy

Tree Numbers

  1. D02w.455w.426w.559w.847w.117.600w
  2. D04w.615w.125.600w

AMA Style

References

  1. National Library of Medicine. Maprotiline. Medical Subject Headings (MeSH). 2026. Unique ID D008376. http://id.nlm.nih.gov/mesh/2026/D008376
  2. Maprotiline. In: Wikipedia. https://en.wikipedia.org/wiki/Maprotiline
  3. Maprotiline. In: Wikidata. https://www.wikidata.org/wiki/Q418361
  4. Maprotiline. In: PubChem Compound. CID 4011. https://pubchem.ncbi.nlm.nih.gov/compound/4011