Structured Summary
Abstract
A diuretic and renal diagnostic aid related to sorbitol. It has little significant energy value as it is largely eliminated from the body before any metabolism can take place. It can be used to treat oliguria associated with kidney failure or other manifestations of inadequate renal function and has been used for determination of glomerular filtration rate. Mannitol is also commonly used as a research tool in cell biological studies, usually to control osmolarity.
Chemical Identity
Chemical Information
- Molecular Formula
- C6H14O6
- Molecular Weight
- 182.17 g/mol
- CAS Registry No.
- 69-65-8
- IUPAC Name
- (2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexol
- InChIKey
- FBPFZTCFMRRESA-KVTDHHQDSA-N
- SMILES
- C([C@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O)O
- MeSH Unique ID
- D008353
- Source
- PubChem CID 6251
MeSH Record
Classification
Broader headings
Narrower headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
3 entry terms
- (L)-Mannitol
- Osmitrol
- Osmofundin
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Mannitol. Medical Subject Headings (MeSH). 2026. Unique ID D008353. http://id.nlm.nih.gov/mesh/2026/D008353
- Mannitol. In: Wikipedia. https://en.wikipedia.org/wiki/Mannitol
- Mannitol. In: Wikidata. https://www.wikidata.org/wiki/Q407646
- Mannitol. In: PubChem Compound. CID 6251. https://pubchem.ncbi.nlm.nih.gov/compound/6251