Chemicals and Drugs

Malonyl Coenzyme A

A coenzyme A derivative which plays a key role in the fatty acid synthesis in the cytoplasmic and microsomal systems.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A coenzyme A derivative which plays a key role in the fatty acid synthesis in the cytoplasmic and microsomal systems.

Chemical Identity

Chemical Information

Molecular Formula
C24H38N7O19P3S
Molecular Weight
853.6 g/mol
CAS Registry No.
524-14-1
IUPAC Name
3-[2-[3-[[(2R)-4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethylsulfanyl]-3-oxopropanoic acid
InChIKey
LTYOQGRJFJAKNA-DVVLENMVSA-N
SMILES
CC(C)(COP(=O)(O)OP(=O)(O)OC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)OP(=O)(O)O)[C@H](C(=O)NCCC(=O)NCCSC(=O)CC(=O)O)O
MeSH Unique ID
D008316
Source
PubChem CID 644066

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

3 entry terms
  • Malonyl CoA
  • CoA, Malonyl
  • Coenzyme A, Malonyl

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

91(78); was see under ACYL COENZYME A 1978-90

MeSH Record

Previous Indexing

  • Coenzyme A (1966-1977)
  • Malonates (1966-1977)

MeSH Hierarchy

Tree Numbers

  1. D03w.633.100.759.646.138.382w.300w.500w
  2. D08.211w.211w.300w.500w
  3. D13.695w.667.138.382w.300w.500w
  4. D13.695w.827w.068.382w.300w.500w

AMA Style

References

  1. National Library of Medicine. Malonyl Coenzyme A. Medical Subject Headings (MeSH). 2026. Unique ID D008316. http://id.nlm.nih.gov/mesh/2026/D008316
  2. Malonyl Coenzyme A. In: Wikipedia. https://en.wikipedia.org/wiki/Malonyl-CoA
  3. Malonyl Coenzyme A. In: Wikidata. https://www.wikidata.org/wiki/Q27095293
  4. Malonyl Coenzyme A. In: PubChem Compound. CID 644066. https://pubchem.ncbi.nlm.nih.gov/compound/644066