Structured Summary
Abstract
A sulfonamide that inhibits the enzyme CARBONIC ANHYDRASE and is used as a topical anti-bacterial agent, especially in burn therapy.
Chemical Identity
Chemical Information
- Molecular Formula
- C7H10N2O2S
- Molecular Weight
- 186.23 g/mol
- CAS Registry No.
- 138-39-6
- IUPAC Name
- 4-(aminomethyl)benzenesulfonamide
- InChIKey
- TYMRLRRVMHJFTF-UHFFFAOYSA-N
- SMILES
- C1=CC(=CC=C1CN)S(=O)(=O)N
- MeSH Unique ID
- D008272
- Source
- PubChem CID 3998
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
10 entry terms
- Maphenid
- 4-Homosulfanilamide
- Bensulfamide
- Mafenide Acetate
- Mafylon
- Marfanil
- Napaltan
- Sulfabenzamine
- Sulfamylon
- 4 Homosulfanilamide
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
1991 (1975); was see under SULFONAMIDES 1975-1990
MeSH Record
Previous Indexing
- Sulfonamides (1970-1974)
- Tosyl Compounds (1973-1974)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Mafenide. Medical Subject Headings (MeSH). 2026. Unique ID D008272. http://id.nlm.nih.gov/mesh/2026/D008272
- Mafenide. In: Wikipedia. https://en.wikipedia.org/wiki/Mafenide
- Mafenide. In: Wikidata. https://www.wikidata.org/wiki/Q3843044
- Mafenide. In: PubChem Compound. CID 3998. https://pubchem.ncbi.nlm.nih.gov/compound/3998