Chemicals and Drugs

Macrophage Colony-Stimulating Factor Receptor

A receptor for MACROPHAGE COLONY-STIMULATING FACTOR encoded by the c-fms proto-oncogene (GENES, FMS). It contains an intrinsic protein-tyrosine kinase activity. When activated the receptor undergoes autophosphorylation, phosphorylation of down-stream signaling molecules and rapid down-regulation.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A receptor for MACROPHAGE COLONY-STIMULATING FACTOR encoded by the c-fms proto-oncogene (GENES, FMS). It contains an intrinsic protein-tyrosine kinase activity. When activated the receptor undergoes autophosphorylation, phosphorylation of down-stream signaling molecules and rapid down-regulation.

MeSH Record

Classification

Broader headings

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MeSH Record

See Also

MeSH Record

Synonyms

29 entry terms
  • Antigens, CD115
  • CD115 Antigen
  • CD115 Antigens
  • CSF-1 Receptor
  • M-CSF Receptor
  • M-CSF Receptors
  • Macrophage Colony-Stimulating Factor Receptors
  • Proto-Oncogene Protein fms
  • Receptor, CSF-1
  • Receptor, Macrophage Colony-Stimulating Factor
  • Receptors, CSF-1
  • Receptors, M-CSF
  • Receptors, Macrophage Colony-Stimulating Factor
  • c-fms Protein
  • fms Proto-Oncogene Protein
  • Antigen, CD115
  • CSF-1 Receptors
  • M CSF Receptor
  • Macrophage Colony Stimulating Factor Receptor
  • Macrophage Colony Stimulating Factor Receptors
  • Proto-Oncogene Protein, fms
  • Receptor, CSF 1
  • Receptor, M-CSF
  • Receptor, Macrophage Colony Stimulating Factor
  • Receptors, CSF 1
  • Receptors, M CSF
  • Receptors, Macrophage Colony Stimulating Factor
  • c fms Protein
  • fms Proto Oncogene Protein

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2000(1991)

MeSH Record

Previous Indexing

  • Proto-Oncogene Proteins (1986-1990)
  • Receptors, Endogenous Substances (1973-1990)

MeSH Hierarchy

Tree Numbers

  1. D08.811w.913w.696w.620.682w.725w.400w.500
  2. D12.776w.476.568w.400w.500
  3. D12.776w.543w.750w.630w.492
  4. D12.776w.543w.750w.705w.852w.150.150
  5. D12.776w.543w.750w.750w.400w.200.200
  6. D12.776w.624.664.700.800

AMA Style

References

  1. National Library of Medicine. Macrophage Colony-Stimulating Factor Receptor. Medical Subject Headings (MeSH). 2026. Unique ID D016186. http://id.nlm.nih.gov/mesh/2026/D016186
  2. Macrophage Colony-Stimulating Factor Receptor. In: Wikidata. https://www.wikidata.org/wiki/Q66058947