Phenomena and Processes

Macrophage Activation

The process of altering the morphology and functional activity of macrophages so that they become avidly phagocytic. It is initiated by lymphokines, such as the macrophage activation factor (MAF) and the macrophage migration-inhibitory factor (MMIF), immune complexes, C3b, and various peptides, polysaccharides, and immunologic adjuvants.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

The process of altering the morphology and functional activity of macrophages so that they become avidly phagocytic. It is initiated by lymphokines, such as the macrophage activation factor (MAF) and the macrophage migration-inhibitory factor (MMIF), immune complexes, C3b, and various peptides, polysaccharides, and immunologic adjuvants.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

3 entry terms
  • Activation, Macrophage
  • Activations, Macrophage
  • Macrophage Activations

MeSH Record

Aspects Covered

6 allowable subheadings

Indexed with the subheadings drug effects, ethics, genetics, immunology, physiology, radiation effects.

MeSH Record

History Note

82

MeSH Record

Previous Indexing

  • Macrophages (1966-1981)

MeSH Hierarchy

Tree Number

  1. G12.287.500

MeSH Record

NLM Classification

QW 690

AMA Style

References

  1. National Library of Medicine. Macrophage Activation. Medical Subject Headings (MeSH). 2026. Unique ID D008262. http://id.nlm.nih.gov/mesh/2026/D008262
  2. Macrophage Activation. In: Wikidata. https://www.wikidata.org/wiki/Q14865489