Anatomy

M Cells

A distinct lineage of epithelial cells, present in MUCOSAL TISSUE, that is responsible for the immune sensing and capture of luminal bacteria and other microparticles. They deliver these microparticles, via TRANSCYTOSIS, to lymphoid tissue for efficient mucosal as well as systemic immune responses. Inflammation-induced M cells arising in response to inflammatory conditions may provide microbial access to tissues without normal M cell-associated immune surveillance tissue.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A distinct lineage of epithelial cells, present in MUCOSAL TISSUE, that is responsible for the immune sensing and capture of luminal bacteria and other microparticles. They deliver these microparticles, via TRANSCYTOSIS, to lymphoid tissue for efficient mucosal as well as systemic immune responses. Inflammation-induced M cells arising in response to inflammatory conditions may provide microbial access to tissues without normal M cell-associated immune surveillance tissue.

MeSH Record

Classification

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MeSH Record

Synonyms

72 entry terms
  • Microfold Cells
  • Cell, M
  • Cell, Microfold
  • Cells, M
  • Cells, Microfold
  • M Cell
  • Microfold Cell
  • Airway M Cells
  • BALT M Cells
  • Bronchiolar M Cells
  • Bronchus-Associated Lymphoid Tissue M Cells
  • Colonic M Cells
  • GALT M Cells
  • Gut-Associated Lymphoid Tissue M Cells
  • Intestinal Epithelial M cells
  • Intestinal Villous M Cells
  • M Cells, Bronchiolar
  • M Cells, Intestinal
  • MALT M Cells
  • Mucosa-Associated Lymphoid Tissue M Cells
  • NALT M Cells
  • Nasopharynx-Associated Lymphoid Tissue M Cells
  • Peyer's Patch M Cells
  • Tonsillar M Cells
  • Airway M Cell
  • BALT M Cell
  • Bronchiolar M Cell
  • Bronchus Associated Lymphoid Tissue M Cells
  • Cell, Airway M
  • Cell, BALT M
  • Cell, Bronchiolar M
  • Cell, Colonic M
  • Cell, GALT M
  • Cell, Intestinal M
  • Cell, MALT M
  • Cell, NALT M
  • Cell, Tonsillar M
  • Cells, Airway M
  • Cells, BALT M
  • Cells, Bronchiolar M
  • Cells, Colonic M
  • Cells, GALT M
  • Cells, Intestinal M
  • Cells, MALT M
  • Cells, NALT M
  • Cells, Tonsillar M
  • Colonic M Cell
  • GALT M Cell
  • Gut Associated Lymphoid Tissue M Cells
  • Intestinal M Cell
  • Intestinal M Cells
  • M Cell, Airway
  • M Cell, BALT
  • M Cell, Bronchiolar
  • M Cell, Colonic
  • M Cell, GALT
  • M Cell, Intestinal
  • M Cell, MALT
  • M Cell, NALT
  • M Cell, Tonsillar
  • M Cells, Airway
  • M Cells, BALT
  • M Cells, Colonic
  • M Cells, GALT
  • M Cells, MALT
  • M Cells, NALT
  • M Cells, Tonsillar
  • MALT M Cell
  • Mucosa Associated Lymphoid Tissue M Cells
  • NALT M Cell
  • Nasopharynx Associated Lymphoid Tissue M Cells
  • Tonsillar M Cell

MeSH Record

Aspects Covered

15 allowable subheadings

Indexed with the subheadings chemistry, classification, cytology, drug effects, enzymology, immunology, metabolism, microbiology, parasitology, pathology, physiology, radiation effects, transplantation, ultrastructure, virology.

MeSH Record

History Note

2023

MeSH Record

Previous Indexing

  • Intestinal Mucosa (1981-2022)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. M Cells. Medical Subject Headings (MeSH). 2026. Unique ID D000092303. http://id.nlm.nih.gov/mesh/2026/D000092303
  2. M Cells. In: Wikipedia. https://en.wikipedia.org/wiki/Microfold_cell
  3. M Cells. In: Wikidata. https://www.wikidata.org/wiki/Q1815955