Phenomena and Processes

MYND Domains

Zinc finger domains (named for myeloid, Nervy and DEAF-1) that occur in a variety of eukaryotic proteins, including RUNT-RELATED TRANSCRIPTION FACTOR 1 . They are characterized by a cluster of cysteine and histidine residues with conserved spacing that forms the zinc-binding motif and have beta-beta-alpha (see BETA-SHEET and ALPHA-HELIX) topology, similar to LIM domains (see LIM DOMAIN PROTEINS) and RING FINGER DOMAINS. MYND domains function as protein interaction motifs and have affinity for PROLINE-RICH PROTEIN DOMAINS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Zinc finger domains (named for myeloid, Nervy and DEAF-1) that occur in a variety of eukaryotic proteins, including RUNT-RELATED TRANSCRIPTION FACTOR 1 . They are characterized by a cluster of cysteine and histidine residues with conserved spacing that forms the zinc-binding motif and have beta-beta-alpha (see BETA-SHEET and ALPHA-HELIX) topology, similar to LIM domains (see LIM DOMAIN PROTEINS) and RING FINGER DOMAINS. MYND domains function as protein interaction motifs and have affinity for PROLINE-RICH PROTEIN DOMAINS.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

9 entry terms
  • MYND Domain
  • MYND Motif
  • Zinc Finger MYND-Type
  • Domain, MYND
  • Domains, MYND
  • MYND Motifs
  • Motif, MYND
  • Motifs, MYND
  • Zinc Finger MYND Type

MeSH Record

Aspects Covered

5 allowable subheadings

Indexed with the subheadings drug effects, genetics, immunology, physiology, radiation effects.

MeSH Record

History Note

2018

MeSH Record

Previous Indexing

  • Protein Structure, Tertiary (1998-2017)

MeSH Hierarchy

Tree Numbers

  1. G02.111.570.820w.709.275.500.985w.375w
  2. G02.111.570.820w.709.275.750w.500.474w

AMA Style

References

  1. National Library of Medicine. MYND Domains. Medical Subject Headings (MeSH). 2026. Unique ID D000074608. http://id.nlm.nih.gov/mesh/2026/D000074608
  2. MYND Domains. In: Wikipedia. https://en.wikipedia.org/wiki/MYND_zinc_finger
  3. MYND Domains. In: Wikidata. https://www.wikidata.org/wiki/Q24779944