Structured Summary
Abstract
A serine-threonine protein kinase that functions in many different processes including the cellular response to PHYSIOLOGICAL STRESS, production of CYTOKINES; ENDOCYTOSIS; CYTOSKELETON dynamics, CELL MIGRATION; and CELL PROLIFERATION. It is phosphorylated by MAPK14 in response to stress, and in turn phosphorylates substrates at a SERINE that is preceded by a large hydrophobic amino acid.
MeSH Record
Classification
Broader headings
Related Concepts
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MeSH Record
Synonyms
10 entry terms
- HSP 27 Kinase
- Heat Shock Protein 27 Kinase
- Heat-Shock Protein 27 Kinase
- MAP-Kinase-Activated Protein Kinase 2
- MAPK Activated Protein Kinase 2
- MAPKAP Kinase 2
- MAPKAP Kinase-2
- MAPKAPK-2
- MAPKAPK2
- HSP25 Kinase
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2026 (1993)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. MAP-Kinase-Activated Kinase 2. Medical Subject Headings (MeSH). 2026. Unique ID D000099190. http://id.nlm.nih.gov/mesh/2026/D000099190
- MAP-Kinase-Activated Kinase 2. In: Wikidata. https://www.wikidata.org/wiki/Q21132836