Chemicals and Drugs

Luteinizing Hormone

A major gonadotropin secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Luteinizing hormone regulates steroid production by the interstitial cells of the TESTIS and the OVARY. The preovulatory LUTEINIZING HORMONE surge in females induces OVULATION, and subsequent LUTEINIZATION of the follicle. LUTEINIZING HORMONE consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the three pituitary glycoprotein hormones (TSH, LH and FSH), but the beta subunit is unique and confers its biological specificity.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A major gonadotropin secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Luteinizing hormone regulates steroid production by the interstitial cells of the TESTIS and the OVARY. The preovulatory LUTEINIZING HORMONE surge in females induces OVULATION, and subsequent LUTEINIZATION of the follicle. LUTEINIZING HORMONE consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the three pituitary glycoprotein hormones (TSH, LH and FSH), but the beta subunit is unique and confers its biological specificity.

MeSH Record

Classification

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MeSH Record

See Also

MeSH Record

Synonyms

9 entry terms
  • ICSH (Interstitial Cell Stimulating Hormone)
  • Interstitial Cell-Stimulating Hormone
  • LH (Luteinizing Hormone)
  • Lutropin
  • Hormone, Interstitial Cell-Stimulating
  • Hormone, Luteinizing
  • Interstitial Cell Stimulating Hormone
  • Luteoziman
  • Luteozyman

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

do not confuse entry term LUTROPIN with PLACENTAL LUTEOTROPIN; for alpha subunit, coordinate with GLYCOPROTEIN HORMONES, ALPHA SUBUNIT; LUTEINIZING HORMONE, BETA SUBUNIT is also available

MeSH Record

History Note

2003 (1968); use ICSH 1963-1967

MeSH Hierarchy

Tree Numbers

  1. D06.472w.699w.322w.576.463w
  2. D06.472w.699w.631.525.343.463w
  3. D12.644w.548w.691.525.343.463w

MeSH Record

NLM Classification

WK 515

AMA Style

References

  1. National Library of Medicine. Luteinizing Hormone. Medical Subject Headings (MeSH). 2026. Unique ID D007986. http://id.nlm.nih.gov/mesh/2026/D007986
  2. Luteinizing Hormone. In: Wikipedia. https://en.wikipedia.org/wiki/Luteinizing_hormone
  3. Luteinizing Hormone. In: Wikidata. https://www.wikidata.org/wiki/Q50265477