Chemicals and Drugs

Lubiprostone

Member of a bicyclic fatty acid class of compounds derived from PROSTAGLANDIN E1 involved in chloride channel gating.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Member of a bicyclic fatty acid class of compounds derived from PROSTAGLANDIN E1 involved in chloride channel gating.

Chemical Identity

Chemical Information

Molecular Formula
C20H32F2O5
Molecular Weight
390.5 g/mol
CAS Registry No.
333963-40-9
IUPAC Name
7-[(2R,4aR,5R,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxo-3,4,4a,5,7,7a-hexahydrocyclopenta[b]pyran-5-yl]heptanoic acid
InChIKey
WGFOBBZOWHGYQH-MXHNKVEKSA-N
SMILES
CCCCC([C@]1(CC[C@H]2[C@H](O1)CC(=O)[C@@H]2CCCCCCC(=O)O)O)(F)F
MeSH Unique ID
D000068238
Source
PubChem CID 157920

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

10 entry terms
  • Prostan-1-oic acid, 16,16-difluoro-11-hydroxy-9,15-dioxo-, (11alpha)-
  • Amitiza
  • RU 0211
  • RU-0211
  • RU0211
  • SPI 0211
  • SPI-0211
  • SPI0211
  • 0211, RU
  • 0211, SPI

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2016 (2005)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Lubiprostone. Medical Subject Headings (MeSH). 2026. Unique ID D000068238. http://id.nlm.nih.gov/mesh/2026/D000068238
  2. Lubiprostone. In: Wikipedia. https://en.wikipedia.org/wiki/Lubiprostone
  3. Lubiprostone. In: Wikidata. https://www.wikidata.org/wiki/Q6695342
  4. Lubiprostone. In: PubChem Compound. CID 157920. https://pubchem.ncbi.nlm.nih.gov/compound/157920