Chemicals and Drugs

Loxapine

An antipsychotic agent used in SCHIZOPHRENIA.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An antipsychotic agent used in SCHIZOPHRENIA.

Chemical Identity

Chemical Information

Molecular Formula
C18H18ClN3O
Molecular Weight
327.8 g/mol
CAS Registry No.
1977-10-2
IUPAC Name
8-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine
InChIKey
XJGVXQDUIWGIRW-UHFFFAOYSA-N
SMILES
CN1CCN(CC1)C2=NC3=CC=CC=C3OC4=C2C=C(C=C4)Cl
MeSH Unique ID
D008152
Source
PubChem CID 3964

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

16 entry terms
  • 2-Chloro-11-(4-methyl-1-piperazinyl)-dibenz(b,f)(1,4)oxazepine
  • Cloxazepine
  • Oxilapine
  • CL-71,563
  • Loxapine Hydrochloride
  • Loxapine Monohydrochloride
  • Loxapine Succinate
  • Loxapinsuccinate
  • Loxipine Maleate
  • Loxipine Succinate
  • Loxitane
  • CL 71,563
  • CL71,563
  • Hydrochloride, Loxapine
  • Maleate, Loxipine
  • Succinate, Loxapine

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(75); was see under DIBENZOXAZEPINES 1975-90

MeSH Record

Previous Indexing

  • Dibenzoxazepines (1971-1974)
  • Piperazines (1971-1974)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Loxapine. Medical Subject Headings (MeSH). 2026. Unique ID D008152. http://id.nlm.nih.gov/mesh/2026/D008152
  2. Loxapine. In: Wikipedia. https://en.wikipedia.org/wiki/Loxapine
  3. Loxapine. In: Wikidata. https://www.wikidata.org/wiki/Q58614
  4. Loxapine. In: PubChem Compound. CID 3964. https://pubchem.ncbi.nlm.nih.gov/compound/3964