Chemicals and Drugs

Loteprednol Etabonate

An androstadiene derivative corticosteroid that is used as an ANTI-ALLERGIC AGENT for the treatment of inflammatory and allergic eye conditions.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An androstadiene derivative corticosteroid that is used as an ANTI-ALLERGIC AGENT for the treatment of inflammatory and allergic eye conditions.

Chemical Identity

Chemical Information

Molecular Formula
C24H31ClO7
Molecular Weight
466.9 g/mol
CAS Registry No.
82034-46-6
IUPAC Name
chloromethyl (8S,9S,10R,11S,13S,14S,17R)-17-ethoxycarbonyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-17-carboxylate
InChIKey
DMKSVUSAATWOCU-HROMYWEYSA-N
SMILES
CCOC(=O)O[C@@]1(CC[C@@H]2[C@@]1(C[C@@H]([C@H]3[C@H]2CCC4=CC(=O)C=C[C@]34C)O)C)C(=O)OCCl
MeSH Unique ID
D000069559
Source
PubChem CID 444025

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

8 entry terms
  • CEHOAC
  • Chloromethyl 17-ethoxycarbonyloxy-11-hydroxy-3-oxoandrosta-1,4-diene-17-carboxylate
  • 17-ethoxycarbonyloxy-11-hydroxy-3-oxoandrosta-1,4-diene-17-carboxylate, Chloromethyl
  • Chloromethyl 17 ethoxycarbonyloxy 11 hydroxy 3 oxoandrosta 1,4 diene 17 carboxylate
  • Etabonate, Loteprednol
  • Alrex
  • Lotemax
  • Loteprednol

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2016 (1990)

MeSH Hierarchy

Tree Number

  1. D04w.210.500w.054.079.129.284w

AMA Style

References

  1. National Library of Medicine. Loteprednol Etabonate. Medical Subject Headings (MeSH). 2026. Unique ID D000069559. http://id.nlm.nih.gov/mesh/2026/D000069559
  2. Loteprednol Etabonate. In: Wikipedia. https://en.wikipedia.org/wiki/Loteprednol_etabonate
  3. Loteprednol Etabonate. In: Wikidata. https://www.wikidata.org/wiki/Q3837481
  4. Loteprednol Etabonate. In: PubChem Compound. CID 444025. https://pubchem.ncbi.nlm.nih.gov/compound/444025