Structured Summary
Abstract
An alkaloid that has actions similar to NICOTINE on nicotinic cholinergic receptors but is less potent. It has been proposed for a variety of therapeutic uses including in respiratory disorders, peripheral vascular disorders, insomnia, and smoking cessation.
Chemical Identity
Chemical Information
- Molecular Formula
- C22H27NO2
- Molecular Weight
- 337.5 g/mol
- CAS Registry No.
- 90-69-7
- IUPAC Name
- 2-[(2R,6S)-6-[(2S)-2-hydroxy-2-phenylethyl]-1-methylpiperidin-2-yl]-1-phenylethanone
- InChIKey
- MXYUKLILVYORSK-HBMCJLEFSA-N
- SMILES
- CN1[C@@H](CCC[C@@H]1CC(=O)C2=CC=CC=C2)C[C@@H](C3=CC=CC=C3)O
- MeSH Unique ID
- D008120
- Source
- PubChem CID 101616
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
Drag nodes to rearrange; hover to trace links; click a node to open its page.
Drug Class
Pharmacological Action
MeSH Record
Synonyms
3 entry terms
- Lobeline Sulfate
- Smokeless
- Sulfate, Lobeline
MeSH Record
Aspects Covered
27 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
Indexing Annotation
/biosyn permitted if by plant
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Lobeline. Medical Subject Headings (MeSH). 2026. Unique ID D008120. http://id.nlm.nih.gov/mesh/2026/D008120
- Lobeline. In: Wikipedia. https://en.wikipedia.org/wiki/Lobeline
- Lobeline. In: Wikidata. https://www.wikidata.org/wiki/Q421905
- Lobeline. In: PubChem Compound. CID 101616. https://pubchem.ncbi.nlm.nih.gov/compound/101616