Chemicals and Drugs

Linezolid

An oxazolidinone and acetamide derived ANTI-BACTERIAL AGENT and PROTEIN SYNTHESIS INHIBITOR that is used in the treatment of GRAM-POSITIVE BACTERIAL INFECTIONS of the skin and respiratory tract.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An oxazolidinone and acetamide derived ANTI-BACTERIAL AGENT and PROTEIN SYNTHESIS INHIBITOR that is used in the treatment of GRAM-POSITIVE BACTERIAL INFECTIONS of the skin and respiratory tract.

Chemical Identity

Chemical Information

Molecular Formula
C16H20FN3O4
Molecular Weight
337.35 g/mol
CAS Registry No.
165800-03-3
IUPAC Name
N-[[(5S)-3-(3-fluoro-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide
InChIKey
TYZROVQLWOKYKF-ZDUSSCGKSA-N
SMILES
CC(=O)NC[C@H]1CN(C(=O)O1)C2=CC(=C(C=C2)N3CCOCC3)F
MeSH Unique ID
D000069349
Source
PubChem CID 441401

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

Drug Class

Pharmacological Action

MeSH Record

Synonyms

10 entry terms
  • Linezolide
  • N-((3-(3-fluoro-4-morpholinylphenyl)-2-oxo-5-oxazolidinyl)methyl)acetamide
  • PNU-100766
  • U 100766
  • U-100766
  • Zyvox
  • 100766, U
  • PNU 100766
  • PNU100766
  • U100766

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2016 (1996)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Linezolid. Medical Subject Headings (MeSH). 2026. Unique ID D000069349. http://id.nlm.nih.gov/mesh/2026/D000069349
  2. Linezolid. In: Wikipedia. https://en.wikipedia.org/wiki/Linezolid
  3. Linezolid. In: Wikidata. https://www.wikidata.org/wiki/Q411377
  4. Linezolid. In: PubChem Compound. CID 441401. https://pubchem.ncbi.nlm.nih.gov/compound/441401