Chemicals and Drugs

Lincomycin

An antibiotic produced by Streptomyces lincolnensis var. lincolnensis. It has been used in the treatment of staphylococcal, streptococcal, and Bacteroides fragilis infections.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An antibiotic produced by Streptomyces lincolnensis var. lincolnensis. It has been used in the treatment of staphylococcal, streptococcal, and Bacteroides fragilis infections.

Chemical Identity

Chemical Information

Molecular Formula
C18H34N2O6S
Molecular Weight
406.5 g/mol
CAS Registry No.
154-21-2
IUPAC Name
(2S,4R)-N-[(1R,2R)-2-hydroxy-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide
InChIKey
OJMMVQQUTAEWLP-KIDUDLJLSA-N
SMILES
CCC[C@@H]1C[C@H](N(C1)C)C(=O)N[C@@H]([C@@H]2[C@@H]([C@@H]([C@H]([C@H](O2)SC)O)O)O)[C@@H](C)O
MeSH Unique ID
D008034
Source
PubChem CID 3000540

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

12 entry terms
  • Lincolnensin
  • Lincomycin A
  • Epilincomycin
  • Lincocin
  • Lincomycin Hydrochloride
  • Lincomycin Monohydrochloride
  • Lincomycin Monohydrochloride, (2S-cis)-Isomer
  • Lincomycin Monohydrochloride, (L-threo)-Isomer
  • Lincomycin Monohydrochloride, Hemihydrate
  • Lincomycin, (2S-cis)-Isomer
  • Lincomycin, (L-threo)-Isomer
  • Hemihydrate Lincomycin Monohydrochloride

MeSH Record

Aspects Covered

26 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

66(64)

MeSH Hierarchy

Tree Numbers

  1. D03w.383.773.532w.500w
  2. D09w.408w.471w.500w

MeSH Record

NLM Classification

QV 350

AMA Style

References

  1. National Library of Medicine. Lincomycin. Medical Subject Headings (MeSH). 2026. Unique ID D008034. http://id.nlm.nih.gov/mesh/2026/D008034
  2. Lincomycin. In: Wikipedia. https://en.wikipedia.org/wiki/Lincomycin
  3. Lincomycin. In: Wikidata. https://www.wikidata.org/wiki/Q423428
  4. Lincomycin. In: PubChem Compound. CID 3000540. https://pubchem.ncbi.nlm.nih.gov/compound/3000540