Chemicals and Drugs

Limonene

A naturally-occurring class of MONOTERPENES which occur as a clear colorless liquid at room temperature. Limonene is the major component in the oil of oranges which has many uses, including as flavor and fragrance. It is recognized as safe in food by the Food and Drug Administration (FDA).

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A naturally-occurring class of MONOTERPENES which occur as a clear colorless liquid at room temperature. Limonene is the major component in the oil of oranges which has many uses, including as flavor and fragrance. It is recognized as safe in food by the Food and Drug Administration (FDA).

Chemical Identity

Chemical Information

Molecular Formula
C10H16
Molecular Weight
136.23 g/mol
CAS Registry No.
138-86-3
IUPAC Name
1-methyl-4-prop-1-en-2-ylcyclohexene
InChIKey
XMGQYMWWDOXHJM-UHFFFAOYSA-N
SMILES
CC1=CCC(CC1)C(=C)C
MeSH Unique ID
D000077222
Source
PubChem CID 22311

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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MeSH Record

Synonyms

21 entry terms
  • 1-Methyl-4-(1-methylethenyl)cyclohexene
  • 4-Mentha-1,8-diene
  • Dipentene
  • Limonene, (+-)-
  • 4 Mentha 1,8 diene
  • (+)-(R)-4-isopropenyl-1-methylcyclohexene
  • (+)-Limonene
  • (-)-Limonene
  • (4R)-1-methyl-4-(1-methylethenyl)cyclohexene
  • (4S)-1-methyl-4-isopropenylcyclohex-1-ene
  • (D)-Limonene
  • (R)-(+)-Limonene
  • (R)-4-isopropenyl-1-methylcyclohexene
  • AISA 5203-L (+)Limonene
  • Cyclohexene, 1-methyl-4-(1-methylethenyl)-, (4R)-
  • Limonene, (+)-
  • Limonene, (+-)-isomer
  • Limonene, (R)-isomer
  • Limonene, (S)-isomer
  • d-Limonene
  • d Limonene

MeSH Record

Aspects Covered

24 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2019(1969)

MeSH Hierarchy

Tree Numbers

  1. D02w.455w.426w.392.368w.367.211.500w
  2. D02w.455w.426w.392.368w.367.379.437w
  3. D02w.455w.849w.575w.157.250w

AMA Style

References

  1. National Library of Medicine. Limonene. Medical Subject Headings (MeSH). 2026. Unique ID D000077222. http://id.nlm.nih.gov/mesh/2026/D000077222
  2. Limonene. In: Wikipedia. https://en.wikipedia.org/wiki/Limonene
  3. Limonene. In: Wikidata. https://www.wikidata.org/wiki/Q278809
  4. Limonene. In: PubChem Compound. CID 22311. https://pubchem.ncbi.nlm.nih.gov/compound/22311