Chemicals and Drugs

Leptin Receptors

Cell surface receptors for obesity factor (LEPTIN), a hormone secreted by the WHITE ADIPOCYTES. Upon leptin-receptor interaction, the signal is mediated through the JAK2/STAT3 pathway to regulate food intake, energy balance and fat storage.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Cell surface receptors for obesity factor (LEPTIN), a hormone secreted by the WHITE ADIPOCYTES. Upon leptin-receptor interaction, the signal is mediated through the JAK2/STAT3 pathway to regulate food intake, energy balance and fat storage.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

16 entry terms
  • Antigens, CD295
  • CD295 Antigens
  • LEPR Protein
  • Leptin Receptor
  • Leptin-Binding Protein
  • OB Receptor
  • Receptor, Leptin
  • Receptors, Leptin
  • Leptin Binding Protein
  • Receptor, OB
  • Leptin Receptor, Large Isoform
  • Leptin Receptor, Small Isoform
  • OBRa Receptor
  • OBRb Receptor
  • Receptor, OBRa
  • Receptor, OBRb

MeSH Record

Aspects Covered

19 allowable subheadings

Indexed with the subheadings administration & dosage, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.

MeSH Record

History Note

2008 (1996)

MeSH Record

Previous Indexing

  • Receptors, Cell Surface (1995-2007)

MeSH Hierarchy

Tree Number

  1. D12.776w.543w.750w.650.500

AMA Style

References

  1. National Library of Medicine. Leptin Receptors. Medical Subject Headings (MeSH). 2026. Unique ID D054411. http://id.nlm.nih.gov/mesh/2026/D054411
  2. Leptin Receptors. In: Wikidata. https://www.wikidata.org/wiki/Q24773154