Chemicals and Drugs

Lenalidomide

A phthalimide and piperidone derivative that has immunomodulatory and antiangiogenic properties. It is used for the treatment of transfusion-dependent anemia in MYELODYSPLASTIC SYNDROMES, and for the treatment of MULTIPLE MYELOMA, and relapsed or refractory MANTLE CELL LYMPHOMA.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A phthalimide and piperidone derivative that has immunomodulatory and antiangiogenic properties. It is used for the treatment of transfusion-dependent anemia in MYELODYSPLASTIC SYNDROMES, and for the treatment of MULTIPLE MYELOMA, and relapsed or refractory MANTLE CELL LYMPHOMA.

Chemical Identity

Chemical Information

Molecular Formula
C13H13N3O3
Molecular Weight
259.26 g/mol
CAS Registry No.
191732-72-6
IUPAC Name
3-(7-amino-3-oxo-1H-isoindol-2-yl)piperidine-2,6-dione
InChIKey
GOTYRUGSSMKFNF-UHFFFAOYSA-N
SMILES
C1CC(=O)NC(=O)C1N2CC3=C(C2=O)C=CC=C3N
MeSH Unique ID
D000077269
Source
PubChem CID 216326

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

8 entry terms
  • 2,6-Piperidinedione, 3-(4-amino-1,3-dihydro-1-oxo-2H- isoindol-2-yl)-
  • 3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione
  • IMiD3 Cpd
  • CC 5013
  • CC-5013
  • CC5013
  • Revimid
  • Revlimid

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2019 (2002)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Lenalidomide. Medical Subject Headings (MeSH). 2026. Unique ID D000077269. http://id.nlm.nih.gov/mesh/2026/D000077269
  2. Lenalidomide. In: Wikipedia. https://en.wikipedia.org/wiki/Lenalidomide
  3. Lenalidomide. In: Wikidata. https://www.wikidata.org/wiki/Q425681
  4. Lenalidomide. In: PubChem Compound. CID 216326. https://pubchem.ncbi.nlm.nih.gov/compound/216326