Structured Summary
Abstract
An autosomal recessive disorder characterized by short stature, defective GROWTH HORMONE RECEPTOR, and failure to generate INSULIN-LIKE GROWTH FACTOR I by GROWTH HORMONE. Laron syndrome is not a form of primary pituitary dwarfism (GROWTH HORMONE DEFICIENCY DWARFISM) but the result of mutation of the human GHR gene on chromosome 5.
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
Drag nodes to rearrange; hover to trace links; click a node to open its page.
MeSH Record
Synonyms
15 entry terms
- Growth Hormone Insensitivity Syndrome
- Growth Hormone Receptor Defect
- Growth Hormone Receptor Deficiency
- Laron Dwarfism
- Laron Type Dwarfism I
- Pituitary Dwarfism II
- Primary GH Resistance
- Primary Growth Hormone Resistance
- Severe GH Insensitivity
- Dwarfism II, Pituitary
- Dwarfism IIs, Pituitary
- Dwarfism, Laron
- GH Resistance, Primary
- Pituitary Dwarfism IIs
- Syndrome, Laron
MeSH Record
Aspects Covered
34 allowable subheadings
Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.
MeSH Record
History Note
2005
MeSH Record
Previous Indexing
- Dwarfism (1976-2004)
- Growth Hormone (1976-2004)
- Receptors, Cell Surface (1976-2004)
- Receptors, Somatotropin (1991-2004)
MeSH Hierarchy
Tree Numbers
MeSH Record
NLM Classification
WK 550
AMA Style
References
- National Library of Medicine. Laron Syndrome. Medical Subject Headings (MeSH). 2026. Unique ID D046150. http://id.nlm.nih.gov/mesh/2026/D046150
- Laron Syndrome. In: Wikipedia. https://en.wikipedia.org/wiki/Laron_syndrome
- Laron Syndrome. In: Wikidata. https://www.wikidata.org/wiki/Q669822