Chemicals and Drugs

Large-Conductance Calcium-Activated Potassium Channels

A major class of calcium activated potassium channels whose members are voltage-dependent. MaxiK channels are activated by either membrane depolarization or an increase in intracellular Ca(2+). They are key regulators of calcium and electrical signaling in a variety of tissues.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A major class of calcium activated potassium channels whose members are voltage-dependent. MaxiK channels are activated by either membrane depolarization or an increase in intracellular Ca(2+). They are key regulators of calcium and electrical signaling in a variety of tissues.

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Classification

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MeSH Record

Synonyms

20 entry terms
  • BK Channel
  • BK Channels
  • Big K Channel
  • Big K Channels
  • Large-Conductance Calcium-Activated Potassium Channel
  • Maxi K Channel
  • Maxi-K Channel
  • Maxi-K Channels
  • MaxiK Channel
  • MaxiK Channels
  • Channel, BK
  • Channel, Big K
  • Channel, Maxi K
  • Channel, Maxi-K
  • Channel, MaxiK
  • K Channel, Big
  • K Channel, Maxi
  • Large Conductance Calcium Activated Potassium Channel
  • Large Conductance Calcium Activated Potassium Channels
  • Maxi K Channels

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2006(2993)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Large-Conductance Calcium-Activated Potassium Channels. Medical Subject Headings (MeSH). 2026. Unique ID D051036. http://id.nlm.nih.gov/mesh/2026/D051036
  2. Large-Conductance Calcium-Activated Potassium Channels. In: Wikipedia. https://en.wikipedia.org/wiki/BK_channel
  3. Large-Conductance Calcium-Activated Potassium Channels. In: Wikidata. https://www.wikidata.org/wiki/Q4835827