Structured Summary
Abstract
Endolysosomal organelles surrounded by multi-lamellar MEMBRANE LIPIDS. They are involved in diverse functions in storage and secretion of cellular LIPIDS. Lamellar bodies in the TYPE 2 PNEUMOCYTES produce and secrete PULMONARY SURFACTANT (e.g., DIPALMITOYL PHOSPHATIDYLCHOLINE). Lamellar bodies in the skin produce and secrete neutral lipids to provide hydrophobic barrier. Pathological accumulation of lamellar bodies are also known in lipid storage diseases (e.g.,LCAT DEFICIENCY; and HERMANSKY-PUDLAK SYNDROME).
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Synonyms
15 entry terms
- Lamellar Granules
- Lamellar Lysosomes
- Membrane Coating Granules
- Membrane-Coating Granules
- Odland Bodies
- Body, Lamellar
- Granule, Lamellar
- Granule, Membrane Coating
- Granule, Membrane-Coating
- Lamellar Body
- Lamellar Granule
- Lamellar Lysosome
- Lysosome, Lamellar
- Membrane Coating Granule
- Membrane-Coating Granule
MeSH Record
Aspects Covered
15 allowable subheadings
Indexed with the subheadings chemistry, classification, drug effects, enzymology, genetics, immunology, metabolism, microbiology, parasitology, pathology, physiology, radiation effects, transplantation, ultrastructure, virology.
MeSH Record
History Note
2022
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AMA Style
References
- National Library of Medicine. Lamellar Bodies. Medical Subject Headings (MeSH). 2026. Unique ID D000088502. http://id.nlm.nih.gov/mesh/2026/D000088502
- Lamellar Bodies. In: Wikipedia. https://en.wikipedia.org/wiki/Lamellar_bodies
- Lamellar Bodies. In: Wikidata. https://www.wikidata.org/wiki/Q4253549