Chemicals and Drugs

Lactoylglutathione Lyase

An enzyme that catalyzes the interconversion of methylglyoxal and lactate, with glutathione serving as a coenzyme. EC 4.4.1.5.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An enzyme that catalyzes the interconversion of methylglyoxal and lactate, with glutathione serving as a coenzyme. EC 4.4.1.5.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

6 entry terms
  • Glyoxalase I
  • Lactoyl Glutathione Lyase
  • Methylglyoxalase
  • Glutathione Lyase, Lactoyl
  • Lyase, Lactoyl Glutathione
  • Lyase, Lactoylglutathione

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

98(75)

MeSH Record

Previous Indexing

  • Glutathione (1973-1974)
  • Glyoxal (1974)
  • Lyases (1973-1974)

MeSH Hierarchy

Tree Number

  1. D08.811w.520w.300.500

AMA Style

References

  1. National Library of Medicine. Lactoylglutathione Lyase. Medical Subject Headings (MeSH). 2026. Unique ID D007791. http://id.nlm.nih.gov/mesh/2026/D007791
  2. Lactoylglutathione Lyase. In: Wikidata. https://www.wikidata.org/wiki/Q24777621