Chemicals and Drugs

Lactose Synthase

An enzyme complex that catalyzes the transfer of GALACTOSE from UDP GALACTOSE to GLUCOSE, forming LACTOSE. The enzyme complex is composed of a B subunit, ALPHA-LACTALBUMIN, which changes the substrate specificity of the A subunit, N-ACETYLLACTOSAMINE SYNTHASE, from N-ACETYLGLUCOSAMINE to glucose making lactose synthesis the preferred reaction.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An enzyme complex that catalyzes the transfer of GALACTOSE from UDP GALACTOSE to GLUCOSE, forming LACTOSE. The enzyme complex is composed of a B subunit, ALPHA-LACTALBUMIN, which changes the substrate specificity of the A subunit, N-ACETYLLACTOSAMINE SYNTHASE, from N-ACETYLGLUCOSAMINE to glucose making lactose synthesis the preferred reaction.

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Classification

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MeSH Record

Synonyms

5 entry terms
  • Lactose Synthetase
  • Synthase, Lactose
  • Synthetase, Lactose
  • N-Acetylgucosamide 1-4 beta Galactosyl Transferase
  • N Acetylgucosamide 1 4 beta Galactosyl Transferase

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

92: was LACTOSE SYNTHETASE 1972-91 (Prov 1972-73)

MeSH Record

Previous Indexing

  • Glucosyltransferases (1966-1971)
  • Lactation (1966-1971)
  • Ligases (1966-1971)
  • Transferases (1966-1971)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Lactose Synthase. Medical Subject Headings (MeSH). 2026. Unique ID D007788. http://id.nlm.nih.gov/mesh/2026/D007788
  2. Lactose Synthase. In: Wikipedia. https://en.wikipedia.org/wiki/Lactose_synthase
  3. Lactose Synthase. In: Wikidata. https://www.wikidata.org/wiki/Q3827587