Chemicals and Drugs

Lactoferrin

An iron-binding protein that was originally characterized as a milk protein. It is widely distributed in secretory fluids and is found in the neutrophilic granules of LEUKOCYTES. The N-terminal part of lactoferrin possesses a serine protease which functions to inactivate the TYPE III SECRETION SYSTEM used by bacteria to export virulence proteins for host cell invasion.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An iron-binding protein that was originally characterized as a milk protein. It is widely distributed in secretory fluids and is found in the neutrophilic granules of LEUKOCYTES. The N-terminal part of lactoferrin possesses a serine protease which functions to inactivate the TYPE III SECRETION SYSTEM used by bacteria to export virulence proteins for host cell invasion.

MeSH Record

Classification

Broader headings

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

1 entry terms
  • Lactotransferrin

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

91(73); was see under LACTOGLOBULINS 1973-90

MeSH Hierarchy

Tree Numbers

  1. D08.811w.277w.656w.300w.760.471
  2. D08.811w.277w.656w.959w.350.471
  3. D09w.400w.430w.887
  4. D12.776w.157w.427w.750.249
  5. D12.776w.256w.159.750.816w.500.507
  6. D12.776w.377w.457.507
  7. D12.776w.395w.507
  8. D12.776w.556w.579w.750.249

MeSH Record

NLM Classification

QU 55.8

AMA Style

References

  1. National Library of Medicine. Lactoferrin. Medical Subject Headings (MeSH). 2026. Unique ID D007781. http://id.nlm.nih.gov/mesh/2026/D007781
  2. Lactoferrin. In: Wikidata. https://www.wikidata.org/wiki/Q24787652