Chemicals and Drugs

Kynurenine 3-Monooxygenase

An NADPH-dependent flavin monooxygenase that plays a key role in the catabolism of TRYPTOPHAN by catalyzing the HYDROXYLATION of KYNURENINE to 3-hydroxykynurenine. It was formerly characterized as EC 1.14.1.2 and EC 1.99.1.5.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An NADPH-dependent flavin monooxygenase that plays a key role in the catabolism of TRYPTOPHAN by catalyzing the HYDROXYLATION of KYNURENINE to 3-hydroxykynurenine. It was formerly characterized as EC 1.14.1.2 and EC 1.99.1.5.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

9 entry terms
  • Kynurenine 3-Hydroxylase
  • Kynurenine Hydroxylase
  • L-Kynurenine-3-Hydroxylase
  • 3-Hydroxylase, Kynurenine
  • 3-Monooxygenase, Kynurenine
  • Hydroxylase, Kynurenine
  • Kynurenine 3 Hydroxylase
  • Kynurenine 3 Monooxygenase
  • L Kynurenine 3 Hydroxylase

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2006(1980); KYNURENINE 1973-1979

MeSH Hierarchy

Tree Number

  1. D08.811w.682w.690w.708.557

AMA Style

References

  1. National Library of Medicine. Kynurenine 3-Monooxygenase. Medical Subject Headings (MeSH). 2026. Unique ID D050601. http://id.nlm.nih.gov/mesh/2026/D050601
  2. Kynurenine 3-Monooxygenase. In: Wikidata. https://www.wikidata.org/wiki/Q411711