Chemicals and Drugs

Ki-1 Antigen

A member of the tumor necrosis factor receptor superfamily that may play a role in the regulation of NF-KAPPA B and APOPTOSIS. It is found on activated T-LYMPHOCYTES; B-LYMPHOCYTES; NEUTROPHILS; EOSINOPHILS; MAST CELLS and NK CELLS. Overexpression of the Ki-1 antigen in hematopoietic malignancies make it clinically useful as a biological tumor marker. Signaling of the receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A member of the tumor necrosis factor receptor superfamily that may play a role in the regulation of NF-KAPPA B and APOPTOSIS. It is found on activated T-LYMPHOCYTES; B-LYMPHOCYTES; NEUTROPHILS; EOSINOPHILS; MAST CELLS and NK CELLS. Overexpression of the Ki-1 antigen in hematopoietic malignancies make it clinically useful as a biological tumor marker. Signaling of the receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.

MeSH Record

Classification

Broader headings

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See Also

MeSH Record

Synonyms

19 entry terms
  • Antigens, CD30
  • Antigens, Ki-1
  • Ber-H2 Antigen
  • Ber-H2 Antigens
  • CD30 Antigen
  • CD30 Antigens
  • Ki-1 Antigens
  • TNFRSF8 Receptor
  • Tumor Necrosis Factor Receptor Superfamily, Member 8
  • Antigen, Ber-H2
  • Antigen, CD30
  • Antigen, Ki-1
  • Antigens, Ber-H2
  • Antigens, Ki 1
  • Ber H2 Antigen
  • Ber H2 Antigens
  • Ki 1 Antigen
  • Ki 1 Antigens
  • Receptor, TNFRSF8

MeSH Record

Aspects Covered

19 allowable subheadings

Indexed with the subheadings administration & dosage, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.

MeSH Record

History Note

2018 (1983)

MeSH Record

Previous Indexing

  • Antigens, CD (1990-1993)
  • Antigens, Differentiation (1988-1993)
  • Antigens, Neoplasm (1985-1993)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.543w.750w.705w.852w.760w.072
  2. D23.050w.285.025
  3. D23.101w.140.055

AMA Style

References

  1. National Library of Medicine. Ki-1 Antigen. Medical Subject Headings (MeSH). 2026. Unique ID D017730. http://id.nlm.nih.gov/mesh/2026/D017730
  2. Ki-1 Antigen. In: Wikidata. https://www.wikidata.org/wiki/Q24720063