Structured Summary
Abstract
A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
Chemical Identity
Chemical Information
- Molecular Formula
- C22H22FN3O3
- Molecular Weight
- 395.4 g/mol
- CAS Registry No.
- 74050-98-9
- IUPAC Name
- 3-[2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl]-1H-quinazoline-2,4-dione
- InChIKey
- FPCCSQOGAWCVBH-UHFFFAOYSA-N
- SMILES
- C1CN(CCC1C(=O)C2=CC=C(C=C2)F)CCN3C(=O)C4=CC=CC=C4NC3=O
- MeSH Unique ID
- D007650
- Source
- PubChem CID 3822
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
7 entry terms
- 3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H,3H)-quinazolinedione
- R-41,468
- R-41468
- R 41,468
- R 41468
- R41,468
- R41468
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
87
MeSH Record
Previous Indexing
- Piperidines (1966-1986)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Ketanserin. Medical Subject Headings (MeSH). 2026. Unique ID D007650. http://id.nlm.nih.gov/mesh/2026/D007650
- Ketanserin. In: Wikipedia. https://en.wikipedia.org/wiki/Ketanserin
- Ketanserin. In: Wikidata. https://www.wikidata.org/wiki/Q415997
- Ketanserin. In: PubChem Compound. CID 3822. https://pubchem.ncbi.nlm.nih.gov/compound/3822