Anatomy

Keratinocytes

Epidermal cells which synthesize keratin and undergo characteristic changes as they move upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. Successive stages of differentiation of the keratinocytes forming the epidermal layers are basal cell, spinous or prickle cell, and the granular cell.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Epidermal cells which synthesize keratin and undergo characteristic changes as they move upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. Successive stages of differentiation of the keratinocytes forming the epidermal layers are basal cell, spinous or prickle cell, and the granular cell.

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Classification

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Synonyms

1 entry terms
  • Keratinocyte

MeSH Record

Aspects Covered

15 allowable subheadings

Indexed with the subheadings chemistry, classification, cytology, drug effects, enzymology, immunology, metabolism, microbiology, parasitology, pathology, physiology, radiation effects, transplantation, ultrastructure, virology.

MeSH Record

History Note

90

MeSH Record

Previous Indexing

  • Epidermis/cytology (1975-1989)
  • Keratin (1968-1989)
  • Skin/cytology (1968-1989)

MeSH Hierarchy

Tree Numbers

  1. A11w.409.500w
  2. A11w.436.397w

MeSH Record

NLM Classification

WR 101

AMA Style

References

  1. National Library of Medicine. Keratinocytes. Medical Subject Headings (MeSH). 2026. Unique ID D015603. http://id.nlm.nih.gov/mesh/2026/D015603
  2. Keratinocytes. In: Wikipedia. https://en.wikipedia.org/wiki/Keratinocyte
  3. Keratinocytes. In: Wikidata. https://www.wikidata.org/wiki/Q1473931