Structured Summary
Abstract
A class of enzymes that inactivate aminocyclitol-aminoglycoside antibiotics (AMINOGLYCOSIDES) by regiospecific PHOSPHORYLATION of the 3' and/or 5' hydroxyl.
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Classification
Broader headings
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MeSH Record
Synonyms
26 entry terms
- Amikacin 3'-Phosphotransferase
- Aminocyclitol Phosphotransferase
- Aminoglycoside 3'-Phosphotransferase Type VIII
- Aminoglycoside Phosphotransferase
- Kanamycin-Neomycin Phosphate Transferase
- Neomycin Phosphotransferase
- 3'-Phosphotransferase, Amikacin
- Amikacin 3' Phosphotransferase
- Aminoglycoside 3' Phosphotransferase Type VIII
- Kanamycin Neomycin Phosphate Transferase
- Kinase, Kanamycin
- Phosphate Transferase, Kanamycin-Neomycin
- Phosphotransferase, Aminocyclitol
- Phosphotransferase, Aminoglycoside
- Phosphotransferase, Neomycin
- Transferase, Kanamycin-Neomycin Phosphate
- APH(3')-IIIa
- APH(3')-IIb
- APHVII
- APT-3'-I and II
- Aminoglycoside 3'-Phosphotransferases (I and II)
- Aminoglycoside Phosphotransferase Type III
- Neomycin Phosphotransferase II
- aphVII Gene Product
- APT 3' I and II
- Phosphotransferase II, Neomycin
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
98; use KANAMYCIN KINASE (NM) 1980-97
MeSH Record
Previous Indexing
- Kanamycin (1976-1980)
- Phosphotransferases (1976-1993)
- Phosphotransferases (Alcohol Group Acceptor) (1994-1997)
MeSH Hierarchy
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AMA Style
References
- National Library of Medicine. Kanamycin Kinase. Medical Subject Headings (MeSH). 2026. Unique ID D019868. http://id.nlm.nih.gov/mesh/2026/D019868
- Kanamycin Kinase. In: Wikipedia. https://en.wikipedia.org/wiki/Kanamycin_kinase
- Kanamycin Kinase. In: Wikidata. https://www.wikidata.org/wiki/Q6360598