Chemicals and Drugs

Kallidin

A decapeptide bradykinin homolog cleaved from kininogen by kallikreins. It is a smooth-muscle stimulant and hypotensive agent that acts by vasodilatation.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A decapeptide bradykinin homolog cleaved from kininogen by kallikreins. It is a smooth-muscle stimulant and hypotensive agent that acts by vasodilatation.

Chemical Identity

Chemical Information

Molecular Formula
C56H85N17O12
Molecular Weight
1188.4 g/mol
CAS Registry No.
342-10-9
IUPAC Name
(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[2-[[(2S)-1-[(2S)-1-[(2S)-2-[[(2S)-2,6-diaminohexanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid
InChIKey
FYSKZKQBTVLYEQ-FSLKYBNLSA-N
SMILES
C1C[C@H](N(C1)C(=O)[C@@H]2CCCN2C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCCN)N)C(=O)NCC(=O)N[C@@H](CC3=CC=CC=C3)C(=O)N[C@@H](CO)C(=O)N4CCC[C@H]4C(=O)N[C@@H](CC5=CC=CC=C5)C(=O)N[C@@H](CCCN=C(N)N)C(=O)O
MeSH Unique ID
D007609
Source
PubChem CID 5311111

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

11 entry terms
  • Lys-Bradykinin
  • Lysine Bradykinin
  • Lysyl Bradykinin
  • N2-L-Lysylbradykinin
  • Bradykinin, Lysine
  • Bradykinin, Lysyl
  • Lys Bradykinin
  • N2 L Lysylbradykinin
  • Kallidin Tetraacetate
  • Kallidin, (D)-Isomer
  • Tetraacetate, Kallidin

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

/biosyn /drug eff /physiol permitted

MeSH Record

History Note

66(64)

MeSH Hierarchy

Tree Numbers

  1. D12.644w.276.812w.169.400w
  2. D12.644w.456w.193.400w
  3. D12.776w.467.812w.169.400w
  4. D23.469.050w.375w.110.400w
  5. D23.529.812w.169.400w

MeSH Record

NLM Classification

QU 68

AMA Style

References

  1. National Library of Medicine. Kallidin. Medical Subject Headings (MeSH). 2026. Unique ID D007609. http://id.nlm.nih.gov/mesh/2026/D007609
  2. Kallidin. In: Wikipedia. https://en.wikipedia.org/wiki/Kallidin
  3. Kallidin. In: Wikidata. https://www.wikidata.org/wiki/Q2398786
  4. Kallidin. In: PubChem Compound. CID 5311111. https://pubchem.ncbi.nlm.nih.gov/compound/5311111