Diseases

Job Syndrome

Primary immunodeficiency syndrome characterized by recurrent infections and hyperimmunoglobulinemia E. Most cases are sporadic. Of the rare familial forms, the dominantly inherited subtype has additional connective tissue, dental and skeletal involvement that the recessive type does not share.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Primary immunodeficiency syndrome characterized by recurrent infections and hyperimmunoglobulinemia E. Most cases are sporadic. Of the rare familial forms, the dominantly inherited subtype has additional connective tissue, dental and skeletal involvement that the recessive type does not share.

MeSH Record

Classification

Related Concepts

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MeSH Record

Synonyms

39 entry terms
  • Buckley Syndrome
  • HIE Syndrome
  • Hyper-IgE Syndrome
  • Hyper-Ige Recurrent Infection Syndrome, Autosomal Dominant
  • Hyperimmunoglobulin E, Recurrent Infection Syndrome
  • Hyperimmunoglobulin E-Recurrent Infection Syndrome
  • Hyperimmunoglobulinemia E Syndrome
  • Job's Syndrome
  • Job-Buckley Syndrome
  • Buckley Syndromes
  • HIE Syndromes
  • Hyper IgE Syndrome
  • Hyper-IgE Syndromes
  • Hyperimmunoglobulin E Recurrent Infection Syndrome
  • Hyperimmunoglobulinemia E Syndromes
  • Job Buckley Syndrome
  • Job Syndromes
  • Job-Buckley Syndromes
  • Jobs Syndrome
  • Syndrome, Job
  • Syndromes, Job
  • HIES, Autosomal Dominant
  • HIES, Autosomal Recessive
  • Hyper-IgE Recurrent Infection Syndrome, Autosomal Recessive
  • Hyper-IgE Syndrome, Autosomal Dominant
  • Hyper-IgE Syndrome, Autosomal Recessive
  • Hyper-Immunoglobulin E Syndrome, Autosomal Dominant
  • Hyper-Immunoglobulin E Syndrome, Autosomal Recessive
  • Autosomal Dominant HIES
  • Autosomal Dominant HIESs
  • Autosomal Recessive HIES
  • Autosomal Recessive HIESs
  • HIESs, Autosomal Dominant
  • HIESs, Autosomal Recessive
  • Hyper IgE Recurrent Infection Syndrome, Autosomal Recessive
  • Hyper IgE Syndrome, Autosomal Dominant
  • Hyper IgE Syndrome, Autosomal Recessive
  • Hyper Immunoglobulin E Syndrome, Autosomal Dominant
  • Hyper Immunoglobulin E Syndrome, Autosomal Recessive

MeSH Record

Aspects Covered

34 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

History Note

2014 (1975);use PHAGOCYTE BACTERICIDAL DYSFUNCTION 1975-1990

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Job Syndrome. Medical Subject Headings (MeSH). 2026. Unique ID D007589. http://id.nlm.nih.gov/mesh/2026/D007589
  2. Job Syndrome. In: Wikipedia. https://en.wikipedia.org/wiki/Hyperimmunoglobulin_E_syndrome
  3. Job Syndrome. In: Wikidata. https://www.wikidata.org/wiki/Q2336873