Chemicals and Drugs

Isoxsuprine

A beta-adrenergic agonist that causes direct relaxation of uterine and vascular smooth muscle. Its vasodilating actions are greater on the arteries supplying skeletal muscle than on those supplying skin. It is used in the treatment of peripheral vascular disease and in premature labor.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A beta-adrenergic agonist that causes direct relaxation of uterine and vascular smooth muscle. Its vasodilating actions are greater on the arteries supplying skeletal muscle than on those supplying skin. It is used in the treatment of peripheral vascular disease and in premature labor.

Chemical Identity

Chemical Information

Molecular Formula
C18H23NO3
Molecular Weight
301.4 g/mol
IUPAC Name
4-[1-hydroxy-2-(1-phenoxypropan-2-ylamino)propyl]phenol
InChIKey
BMUKKTUHUDJSNZ-UHFFFAOYSA-N
SMILES
CC(COC1=CC=CC=C1)NC(C)C(C2=CC=C(C=C2)O)O
MeSH Unique ID
D007556
Source
PubChem CID 3783

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

3 entry terms
  • Duvadilan
  • Isoxsuprine Hydrochloride
  • Hydrochloride, Isoxsuprine

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

73(72)

MeSH Record

Previous Indexing

  • Amino Alcohols (1966-1971)
  • Sympathomimetics (1966-1971)

MeSH Hierarchy

Tree Numbers

  1. D02w.033w.100w.624w.427w
  2. D02w.033w.755.624w.427w
  3. D02w.092w.471.683w.560w

AMA Style

References

  1. National Library of Medicine. Isoxsuprine. Medical Subject Headings (MeSH). 2026. Unique ID D007556. http://id.nlm.nih.gov/mesh/2026/D007556
  2. Isoxsuprine. In: Wikipedia. https://en.wikipedia.org/wiki/Isoxsuprine
  3. Isoxsuprine. In: Wikidata. https://www.wikidata.org/wiki/Q1117888
  4. Isoxsuprine. In: PubChem Compound. CID 3783. https://pubchem.ncbi.nlm.nih.gov/compound/3783