Analytical, Diagnostic and Therapeutic Techniques, and Equipment

Isotachophoresis

A nonlinear electrophoretic technique used to separate a variety of ionic compounds, ranging from small metal ions to large molecules like proteins. Unlike linear zone electrophoresis in which separating solute bands continually spread by diffusion or dispersion, isotachophoresis forms self-sharpening, adjacent zones of substantially pure solute whose concentrations often exceed several mgs/ml. In isotachophoresis a multianalyte sample is introduced between the leading electrolyte and the terminating electrolyte where the sample ions have lower electrophoretic mobilities than the leading ion but larger than the terminating ion. (From Isotachophoresis on the AES Web Site [Internet]. Madison, WI: The American Electrophoresis Society; c2000-2008 [cited 2009 Aug 20]. Available from http://www.aesociety.org/areas/isotachophoresis.php)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A nonlinear electrophoretic technique used to separate a variety of ionic compounds, ranging from small metal ions to large molecules like proteins. Unlike linear zone electrophoresis in which separating solute bands continually spread by diffusion or dispersion, isotachophoresis forms self-sharpening, adjacent zones of substantially pure solute whose concentrations often exceed several mgs/ml. In isotachophoresis a multianalyte sample is introduced between the leading electrolyte and the terminating electrolyte where the sample ions have lower electrophoretic mobilities than the leading ion but larger than the terminating ion. (From Isotachophoresis on the AES Web Site [Internet]. Madison, WI: The American Electrophoresis Society; c2000-2008 [cited 2009 Aug 20]. Available from http://www.aesociety.org/areas/isotachophoresis.php)

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Synonyms

2 entry terms
  • Displacement Electrophoresis
  • Electrophoresis, Displacement

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Aspects Covered

10 allowable subheadings

Indexed with the subheadings classification, economics, ethics, history, instrumentation, methods, standards, statistics & numerical data, trends, veterinary.

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History Note

2011; use Electrophoresis 1985-2010

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Previous Indexing

  • Electrophoresis or specifics (1970-2010)

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References

  1. National Library of Medicine. Isotachophoresis. Medical Subject Headings (MeSH). 2026. Unique ID D057625. http://id.nlm.nih.gov/mesh/2026/D057625
  2. Isotachophoresis. In: Wikipedia. https://en.wikipedia.org/wiki/Isotachophoresis
  3. Isotachophoresis. In: Wikidata. https://www.wikidata.org/wiki/Q238614