Chemicals and Drugs

Isosorbide

1,4:3,6-Dianhydro D-glucitol. Chemically inert osmotic diuretic used mainly to treat hydrocephalus; also used in glaucoma.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

1,4:3,6-Dianhydro D-glucitol. Chemically inert osmotic diuretic used mainly to treat hydrocephalus; also used in glaucoma.

Chemical Identity

Chemical Information

Molecular Formula
C6H10O4
Molecular Weight
146.14 g/mol
CAS Registry No.
652-67-5
IUPAC Name
(3S,3aR,6R,6aR)-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-3,6-diol
InChIKey
KLDXJTOLSGUMSJ-JGWLITMVSA-N
SMILES
C1[C@H]([C@@H]2[C@H](O1)[C@H](CO2)O)O
MeSH Unique ID
D007547
Source
PubChem CID 12597

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

1 entry terms
  • Dianhydrosorbitol

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

a diuretic

MeSH Record

History Note

91(75); was see under SORBITOL 1975-90

MeSH Record

Previous Indexing

  • Ethers, Cyclic (1974)
  • Sorbitol (1974)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Isosorbide. Medical Subject Headings (MeSH). 2026. Unique ID D007547. http://id.nlm.nih.gov/mesh/2026/D007547
  2. Isosorbide. In: Wikipedia. https://en.wikipedia.org/wiki/Isosorbide
  3. Isosorbide. In: Wikidata. https://www.wikidata.org/wiki/Q1243800
  4. Isosorbide. In: PubChem Compound. CID 12597. https://pubchem.ncbi.nlm.nih.gov/compound/12597