Structured Summary
Abstract
A multifunctional iron-sulfur protein that is both an iron regulatory protein and cytoplasmic form of aconitate hydratase. It binds to iron regulatory elements found on mRNAs involved in iron metabolism and regulates their translation. Its rate of degradation is increased in the presence of IRON.
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Classification
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MeSH Record
Synonyms
7 entry terms
- IRE-BP2
- IREB2 Protein
- IRP-2 RNA-binding protein
- IRP2 Protein
- Iron-Responsive-Element Binding Protein 2
- IRP 2 RNA binding protein
- RNA-binding protein, IRP-2
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2003; for IRON REGULATORY PROTEIN 2, IRE-BP2 & IRP-2 RNA-BINDING PROTEIN use IRON-REGULATORY PROTEINS (NM) 1995-2002
MeSH Record
Previous Indexing
- Iron-Sulfur Proteins (1995-2002)
- Ribonucleoproteins (1995-2002)
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Tree Numbers
AMA Style
References
- National Library of Medicine. Iron Regulatory Protein 2. Medical Subject Headings (MeSH). 2026. Unique ID D035942. http://id.nlm.nih.gov/mesh/2026/D035942
- Iron Regulatory Protein 2. In: Wikidata. https://www.wikidata.org/wiki/Q21118453