Diseases

Iridocorneal Endothelial Syndrome

A grouping of three closely linked conditions: iris nevus (or Cogan-Reese) syndrome, Chandler Syndrome, and essential (progressive) iris atrophy. The most common features of this syndrome are the movement of endothelial cells off the cornea onto the iris leading to corneal swelling, distortion of the iris, and variable degrees of distortion of the pupil. The abnormal cell movement plugs fluid outflow channels of the eye causing GLAUCOMA.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A grouping of three closely linked conditions: iris nevus (or Cogan-Reese) syndrome, Chandler Syndrome, and essential (progressive) iris atrophy. The most common features of this syndrome are the movement of endothelial cells off the cornea onto the iris leading to corneal swelling, distortion of the iris, and variable degrees of distortion of the pupil. The abnormal cell movement plugs fluid outflow channels of the eye causing GLAUCOMA.

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

MeSH Record

See Also

MeSH Record

Synonyms

7 entry terms
  • ICE Syndrome
  • Endothelial Syndrome, Iridocorneal
  • Iridocorneal Endothelial Syndromes
  • Chandler Syndrome
  • Chandler's Syndrome
  • Iris Atrophy with Corneal Edema and Glaucoma
  • Chandlers Syndrome

MeSH Record

Aspects Covered

35 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

History Note

2010

MeSH Record

Previous Indexing

  • Corneal Diseases (1979-2009)
  • Iris Diseases (1979-2009)

MeSH Hierarchy

Tree Numbers

  1. C11w.204.497w
  2. C11w.941.375.322w

AMA Style

References

  1. National Library of Medicine. Iridocorneal Endothelial Syndrome. Medical Subject Headings (MeSH). 2026. Unique ID D057129. http://id.nlm.nih.gov/mesh/2026/D057129
  2. Iridocorneal Endothelial Syndrome. In: Wikipedia. https://en.wikipedia.org/wiki/Iridocorneal_endothelial_syndrome
  3. Iridocorneal Endothelial Syndrome. In: Wikidata. https://www.wikidata.org/wiki/Q17121503