Chemicals and Drugs

Ionophores

Chemical agents that increase the permeability of biological or artificial lipid membranes to specific ions. Most ionophores are relatively small organic molecules that act as mobile carriers within membranes or coalesce to form ion permeable channels across membranes. Many are antibiotics, and many act as uncoupling agents by short-circuiting the proton gradient across mitochondrial membranes.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Chemical agents that increase the permeability of biological or artificial lipid membranes to specific ions. Most ionophores are relatively small organic molecules that act as mobile carriers within membranes or coalesce to form ion permeable channels across membranes. Many are antibiotics, and many act as uncoupling agents by short-circuiting the proton gradient across mitochondrial membranes.

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Synonyms

1 entry terms
  • Ionophore

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Aspects Covered

22 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

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History Note

76

MeSH Record

Previous Indexing

  • Antibiotics (1966-1975)
  • Biological Transport (1966-1975)
  • Uncoupling Agents (1972-1975)

MeSH Hierarchy

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AMA Style

References

  1. National Library of Medicine. Ionophores. Medical Subject Headings (MeSH). 2026. Unique ID D007476. http://id.nlm.nih.gov/mesh/2026/D007476
  2. Ionophores. In: Wikipedia. https://en.wikipedia.org/wiki/Ionophore
  3. Ionophores. In: Wikidata. https://www.wikidata.org/wiki/Q415168