Phenomena and Processes

Ion Channel Gating

The opening and closing of ion channels due to a stimulus. The stimulus can be a change in membrane potential (voltage-gated), drugs or chemical transmitters (ligand-gated), or a mechanical deformation. Gating is thought to involve conformational changes of the ion channel which alters selective permeability.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

The opening and closing of ion channels due to a stimulus. The stimulus can be a change in membrane potential (voltage-gated), drugs or chemical transmitters (ligand-gated), or a mechanical deformation. Gating is thought to involve conformational changes of the ion channel which alters selective permeability.

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Classification

Broader headings

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See Also

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Synonyms

3 entry terms
  • Gating, Ion Channel
  • Gatings, Ion Channel
  • Ion Channel Gatings

MeSH Record

Aspects Covered

5 allowable subheadings

Indexed with the subheadings drug effects, genetics, immunology, physiology, radiation effects.

MeSH Record

Indexing Annotation

do not confuse with SENSORY GATING

MeSH Record

History Note

90

MeSH Record

Previous Indexing

  • Electric Conductivity (1966-1989)
  • Electrophysiology (1966-1989)
  • Ion Channels (1979-1989)
  • Membrane Potentials (1966-1989)

MeSH Hierarchy

Tree Numbers

  1. G02.111.820w.400
  2. G04.835w.400
  3. G07.265.625

MeSH Record

NLM Classification

QU 55.7

AMA Style

References

  1. National Library of Medicine. Ion Channel Gating. Medical Subject Headings (MeSH). 2026. Unique ID D015640. http://id.nlm.nih.gov/mesh/2026/D015640
  2. Ion Channel Gating. In: Wikidata. https://www.wikidata.org/wiki/Q71150414