Anatomy

Intraepithelial Lymphocytes

T Lymphocytes with limited diversity of receptors (e.g., ALPHA E INTEGRINS) in the epidermis of the skin and the mucosal linings. They recognize common microbes via T-CELL RECEPTORS and PATHOGEN-ASSOCIATED MOLECULAR PATTERN MOLECULES and function as effector cells for INNATE IMMUNITY. Activation of intraepithelial lymphocytes is a marker for various gastrointestinal diseases (e.g., CELIAC DISEASE; HAIRY CELL LEUKEMIA; and ENTEROPATHY-ASSOCIATED T-CELL LYMPHOMA).

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

T Lymphocytes with limited diversity of receptors (e.g., ALPHA E INTEGRINS) in the epidermis of the skin and the mucosal linings. They recognize common microbes via T-CELL RECEPTORS and PATHOGEN-ASSOCIATED MOLECULAR PATTERN MOLECULES and function as effector cells for INNATE IMMUNITY. Activation of intraepithelial lymphocytes is a marker for various gastrointestinal diseases (e.g., CELIAC DISEASE; HAIRY CELL LEUKEMIA; and ENTEROPATHY-ASSOCIATED T-CELL LYMPHOMA).

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

25 entry terms
  • Gamma Delta T Cell
  • Gamma Delta T Cells
  • Gamma Delta T Lymphocyte
  • Gamma Delta T Lymphocytes
  • Intraepithelial Lymphocyte
  • Intraepithelial T Cell
  • Intraepithelial T Cells
  • Intraepithelial T Lymphocyte
  • Intraepithelial T Lymphocytes
  • Mucosal T Cell
  • Mucosal T Cells
  • Mucosal T Lymphocyte
  • Mucosal T Lymphocytes
  • Lymphocyte, Intraepithelial
  • Lymphocytes, Intraepithelial
  • T Cell, Intraepithelial
  • T Cell, Mucosal
  • T Cells, Intraepithelial
  • T Cells, Mucosal
  • T Lymphocyte, Intraepithelial
  • T Lymphocyte, Mucosal
  • T Lymphocytes, Intraepithelial
  • T Lymphocytes, Mucosal
  • Dendritic Epithelial T Cell
  • Dendritic Epithelial T Cells

MeSH Record

Aspects Covered

15 allowable subheadings

Indexed with the subheadings chemistry, classification, cytology, drug effects, enzymology, immunology, metabolism, microbiology, parasitology, pathology, physiology, radiation effects, transplantation, ultrastructure, virology.

MeSH Record

History Note

2018

MeSH Record

Previous Indexing

  • T-Lymphocytes (1977-2017)

MeSH Hierarchy

Tree Numbers

  1. A11w.118w.637w.555w.567w.550.500.050w
  2. A11w.118w.637w.555w.567w.569w.500.050w
  3. A15.145w.229w.637w.555w.567w.550.500.050w
  4. A15.145w.229w.637w.555w.567w.569w.500.050w
  5. A15.382w.490w.555w.567w.550.500.050w
  6. A15.382w.490w.555w.567w.569w.500.050w

AMA Style

References

  1. National Library of Medicine. Intraepithelial Lymphocytes. Medical Subject Headings (MeSH). 2026. Unique ID D000075942. http://id.nlm.nih.gov/mesh/2026/D000075942
  2. Intraepithelial Lymphocytes. In: Wikipedia. https://en.wikipedia.org/wiki/Intraepithelial_lymphocyte
  3. Intraepithelial Lymphocytes. In: Wikidata. https://www.wikidata.org/wiki/Q17100626