Chemicals and Drugs

Interleukin-4 Receptors

Receptors present on a wide variety of hematopoietic and non-hematopoietic cell types that are specific for INTERLEUKIN-4. They are involved in signaling a variety of immunological responses related to allergic INFLAMMATION including the differentiation of TH2 CELLS and the regulation of IMMUNOGLOBULIN E production. Two subtypes of receptors exist and are referred to as the TYPE I INTERLEUKIN-4 RECEPTOR and the TYPE II INTERLEUKIN-4 RECEPTOR. Each receptor subtype is defined by its unique subunit composition.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Receptors present on a wide variety of hematopoietic and non-hematopoietic cell types that are specific for INTERLEUKIN-4. They are involved in signaling a variety of immunological responses related to allergic INFLAMMATION including the differentiation of TH2 CELLS and the regulation of IMMUNOGLOBULIN E production. Two subtypes of receptors exist and are referred to as the TYPE I INTERLEUKIN-4 RECEPTOR and the TYPE II INTERLEUKIN-4 RECEPTOR. Each receptor subtype is defined by its unique subunit composition.

MeSH Record

Classification

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MeSH Record

Synonyms

18 entry terms
  • IL-4 Receptor
  • IL-4 Receptors
  • IL4 Receptor
  • IL4 Receptors
  • Interleukin 4 Receptor
  • Interleukin-4 Receptor
  • Receptors, IL-4
  • Receptors, Interleukin-4
  • IL 4 Receptor
  • IL 4 Receptors
  • Interleukin 4 Receptors
  • Receptor, IL-4
  • Receptor, IL4
  • Receptor, Interleukin 4
  • Receptor, Interleukin-4
  • Receptors, IL 4
  • Receptors, IL4
  • Receptors, Interleukin 4

MeSH Record

Aspects Covered

19 allowable subheadings

Indexed with the subheadings administration & dosage, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.

MeSH Record

Indexing Annotation

RECEPTORS, INTERLEUKIN-4 TYPE I and RECEPTORS, INTERLEUKIN-4 TYPE II are also available

MeSH Record

History Note

1998(1986)

MeSH Record

Previous Indexing

  • Antigens, CD (1990-1997)
  • Receptors, Interleukin (1994-1997)
  • Receptors, Mitogen (1986-1994)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Interleukin-4 Receptors. Medical Subject Headings (MeSH). 2026. Unique ID D019948. http://id.nlm.nih.gov/mesh/2026/D019948
  2. Interleukin-4 Receptors. In: Wikidata. https://www.wikidata.org/wiki/Q21116060