Chemicals and Drugs

Interleukin-4

A soluble factor produced by activated T-LYMPHOCYTES that induces the expression of MHC CLASS II GENES and FC RECEPTORS on B-LYMPHOCYTES and causes their proliferation and differentiation. It also acts on T-lymphocytes, MAST CELLS, and several other hematopoietic lineage cells.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A soluble factor produced by activated T-LYMPHOCYTES that induces the expression of MHC CLASS II GENES and FC RECEPTORS on B-LYMPHOCYTES and causes their proliferation and differentiation. It also acts on T-lymphocytes, MAST CELLS, and several other hematopoietic lineage cells.

MeSH Record

Classification

Broader headings

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

See Also

MeSH Record

Synonyms

21 entry terms
  • B Cell Stimulatory Factor-1
  • B-Cell Growth Factor-1
  • B-Cell Growth Factor-I
  • B-Cell Proliferating Factor
  • B-Cell Stimulating Factor-1
  • B-Cell Stimulatory Factor 1
  • B-Cell Stimulatory Factor-1
  • BCGF-1
  • BSF-1
  • Binetrakin
  • IL-4
  • IL4
  • MCGF-2
  • Mast Cell Growth Factor-2
  • B Cell Growth Factor 1
  • B Cell Growth Factor I
  • B Cell Proliferating Factor
  • B Cell Stimulating Factor 1
  • B Cell Stimulatory Factor 1
  • Interleukin 4
  • Mast Cell Growth Factor 2

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

90; B-CELL GROWTH FACTOR was see INTERLEUKIN-4 1990-96

MeSH Record

Previous Indexing

  • Interleukins (1988-1989)
  • Lymphokines (1974-1987)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Interleukin-4. Medical Subject Headings (MeSH). 2026. Unique ID D015847. http://id.nlm.nih.gov/mesh/2026/D015847
  2. Interleukin-4. In: Wikidata. https://www.wikidata.org/wiki/Q24780359